Mark and Catherine Winkler Assistant Professor of Airway Biology
Harvard T.H. Chan School of Public Health
Jin-Ah Park holds a Bachelor of Science in Chemistry and Master of Science in Chemistry from Chonbuk National University, Korea, and a PhD in Toxicology (minoring in Immunology) from North Carolina State University.
Park’s research focuses on the mechanisms underlying airway remodeling in asthma. Specifically, her major research interests include the role of extracellular vesicles, the mechanotransduction paradigm, and the biochemical and biophysical characteristics of the airway epithelium in asthma pathogenesis. She has been instrumental in cutting-edge research that uncovered the unjamming transition of airway epithelial cells in asthma.
She is a recent awardee of two career development grants, including a Scientist Development Grant from the American Heart Association and a Parker B. Francis Fellowship from the Francis Family Foundation. Known as a leader in the field of asthma research, she received an Ann Woolcock Memorial Award for outstanding contributions and future promise in asthma research from the American Thoracic Society (ATS). She is a member of the editorial board of the American Journal of Respiratory Cell and Molecular Biology.
Park JA, Atia L, Mitchel JA, Butler JP, Fredberg JJ. Collective migration and cell jamming in asthma, cancer and development. Journal of Cell Science. 2016, 129(18):3375-83.
Mitchel JA, Antoniak S, Lee JH, Kim SH, McGill M, Kasahara DI, Randell SH, Israel E, Shore SA, Mackman N, Park JA. IL-13 Augments compressive stress-induced tissue factor expression in human airway epithelial cells. American Journal of Respiratory Cellular and Molecular Biology. 2016, Apr;54(4):524-31.
Park JA, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R, Burger B, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Unjamming and cell shape in the asthmatic airway epithelium. Nature Materials, 2015, Oct;14(10):1040-8.
Park JA, Sharif AS, Tschumperlin DJ, Lau L, Limbrey R, Howarth PH, Drazen JM. TF-bearing exosome from mechanically-stimulated human bronchial epithelial cells in vitro and in vivo. Journal of Allergy and Clinical Immunology. 2012, Dec;130(6):1375-83.
A complete list of published work is available in her bibliography.
Faculty website: https://www.hsph.harvard.edu/park-lab/